1; 2; First Prev 2 of 2 Go to page. Four of the five sites temporarily closed while an investigation took place. As of November 2021, 11 candidate vaccines for COVID-19 have been approved by the World Health Organization for mass vaccination after leaving phase 3 of clinical studies. 2021;42(9):35379. "It's really hard whether to say this is something that happened independently or is it complications from the vaccine until you can look at large populations of people and look at their side. 2022;73(1):8787. The most common symptoms of long COVID are: extreme tiredness (fatigue) shortness of breath. McGonagle D, De Marco G, Bridgewood C. Mechanisms of immunothrombosis in vaccine-induced thrombotic thrombocytopenia (VITT) compared to natural SARS-CoV-2 infection. Persons with allergic-like symptoms and those who received diphenhydramine or epinephrine were excluded. Thirteen patients were transported to an emergency department for further medical evaluation; all five patients with available follow-up information were released later that day. 2021. https://doi.org/10.7759/cureus.16624. Centers for Disease Control and Prevention. All rights reserved. Adverse reactions after the second dose of the vaccine are reported more than in the first dose [5]. COVID-19 vaccination can sometimes have severe side effects on nervous system, including the brain, spinal cord, cranial nerves, and peripheral nerves, and has been shown to have adverse vascular, metabolic, inflammatory, and functional effects on the brain [1]. pain at the site of the injection. 32 In addition, you might benefit from connecting with others in a support group and sharing resources. If you're having symptoms of post-COVID-19 syndrome, talk to your health care provider. Feb 6, 2021 #41 stout1 said: . One hundred twenty-three (19%) reports indicated that the recipient had a history of syncope associated with receiving injections or needle aversion. endorsement of these organizations or their programs by CDC or the U.S. Romn GC, Gracia F, Torres A, Palacios A, Gracia K, Harris D. Acute transverse myelitis (ATM): clinical review of 43 patients with COVID-19-associated ATM and 3 post-vaccination ATM serious adverse events with the ChAdOx1 nCoV-19 vaccine (AZD1222). PubMed Central https://www.cdc.gov/coronavirus/2019-ncov/hcp/clinical-care/post-covid-conditions.html. Article Neurol Sci. . J Eur Acad Dermatol Venereol. Her PCP thought she was having a panic attack and gave her Xanax. People who had severe illness with COVID-19 might experience organ damage affecting the heart, kidneys, skin and brain. But as I sat for the required 15 minutes of observation time, a wave of something engulfed my body. MMWR Morb Mortal Wkly Rep 2021;70:6516. COV2.S vaccination. Cite this article. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. Fatigue. Common COVID-19 vaccine side effects include: Redness or soreness at injection site. Accessed May 6, 2022. Successful treatment of thrombotic thrombocytopenia with cerebral sinus venous thrombosis following Ad26. 2021;12:879. 31 On the contrary, people in poor and developing countries, including health workers, have not received full COVID-19 immunization. Syncopal events after influenza vaccination were reported most frequently among persons aged 1829 years; the median patient age was 26 years (range=1888 years). Nayere Askari. Khayat-Khoei M, Bhattacharyya S, Katz J, Harrison D, Tauhid S, Bruso P, Houtchens MK, Edwards KR, Bakshi R. COVID-19 mRNA vaccination leading to CNS inflammation: a case series. Other types of side effects from the coronavirus vaccines are not unusual. Supportive care included placing the person supine and offering hydration and food. 2021;1: 100019. All vaccines could cause some degree of reaction, and the same is true for COVID-19 vaccines. 2021. https://doi.org/10.1136/jnnp-2021-327027. In addition, in mass vaccination situations, an anxiety-related event witnessed by others on-site or reported through media coverage might provoke additional anxiety-induced episodes (4). Neurological complications of COVID-19: Guillain-Barre syndrome following Pfizer COVID-19 vaccine. J Med Virol. Most events resolved within 15 minutes with supportive care. Thirteen (20%) patients were transported to an emergency department for further medical evaluation; among these, all five for whom follow-up information was available were released from medical care on the same day. The vast majority who talked about their COVID-19 vaccine side effects or reactions described them as similar to a flu shot. On April 30, 2021, this report was posted online as an MMWR Early Release. Jul 27, 2020 1,690 1,816 113. Crit Care Med. 2021;17(10):34813. In November 2021 in The New England Journal of Medicine, he proposed that an autoimmune mechanism triggered by the SARS-CoV-2 spike protein might explain both Long Covid symptoms and some rare vaccine side effects, and he called for more basic research to probe possible connections. 2021;359: 577686. Part of An anxiety-related event was defined as any of the following occurring in a person during the 15-minute postvaccination observation period at any of the five sites reporting these clusters: tachycardia (rapid heart rate), hyperventilation (rapid breathing), dyspnea (difficulty breathing), chest pain, paresthesia (numbness or tingling), light-headedness, hypotension (low blood pressure), headache, pallor, or syncope (2). One study published by the CDC reports that from March 2020 to January 2021, patients with COVID-19 had nearly 16 times the risk for myocarditis compared with patients who did not have COVID-19. Mikkelsen ME, et al. According to a recent report on the Sputnik vaccine, side effects are included headache, joint pain, fever, and flu-like symptoms [14]. MMWR and Morbidity and Mortality Weekly Report are service marks of the U.S. Department of Health and Human Services. These activities were reviewed by CDC and were conducted consistent with applicable federal law and CDC policy.. 2021. https://doi.org/10.2139/ssrn.3841558. 2021;358: 577606. People with severe symptoms of COVID-19 often need to be treated in a hospital intensive care unit. part 46, 21 C.F.R. "We don't know why that is, how long these symptoms will last or if there are effective ways to treat them. Acute transverse myelitis associated with COVID-19 vaccine: a case report. Article J Autoimmun. Early outcomes of bivalirudin therapy for thrombotic thrombocytopenia and cerebral venous sinus thrombosis after Ad26. All COVID-19 vaccine recipients should be observed for at least 15 minutes after vaccination for anxiety-related and other events (e.g., anaphylaxis or immediate allergic reaction) occurring shortly after vaccination. Headache. A weakened immune system, such as from an autoimmune disorder, can put you at a higher risk of developing. How well do face masks protect against COVID-19? Chronic fatigue syndrome involves extreme fatigue that worsens with physical or mental activity, but doesn't improve with rest. https://doi.org/10.1186/s40001-023-00992-0, DOI: https://doi.org/10.1186/s40001-023-00992-0. mmwrq@cdc.gov. 2021. https://doi.org/10.1016/j.nrleng.2021.05.002. More than half said they experienced a sore arm, fatigue or headache. VST is the most severe disorder that should be diagnosed and controlled immediately. Cureus. Swollen lymph nodes (typically manifests as a lump in your armpit or above your collarbone) The side effects are similar for the three vaccines and are an indication that the vaccines are helping to build protection against disease. In clinical trials, two participants in their . According to the WHO, in the case of side effects of inactivated virus-based vaccines, especially Sinopharm, the most common local and systemic adverse reactions are injection site reactions, fatigue, fever, headache, and allergic dermatitis, which are self-limiting, and the person does not need to be hospitalized [11, 12]. But the side effect. 2021;114(7):5312. You might be more likely to have post-COVID-19 syndrome if: Post-COVID-19 syndrome also appears to be more common in adults than in children and teens. J Neurol Sci. During March and April 2021, among 7.98 million doses of Janssen COVID-19 vaccine administered in the United States, the VAERS reporting rate of syncope after Janssen COVID-19 vaccination was 8.2 per 100,000 doses. Ann Neurol. PubMed Prevalence of anxiety-related adverse events ranged from 5.2 to 13.5 per 1,000 persons vaccinated. World J Clin Cases. Inflammation Res. 2021. https://doi.org/10.9734/ijmpcr/2021/v14i130124. Ann Med Surg. I truly believe this is a side effect of the vaccine. muscle or joint aches. Among people age 65 and older, 1 in 4 has at least one medical condition that might be due to COVID-19. Inflammation and problems with the immune system can also happen. Nausea. I am about 2 1/2 weeks in and this is ridiculous with the anxiety and or panic attacks I am having and feeling like garbage. COVID-19 vaccine-induced encephalitis and status epilepticus. 2021;208: 106887. MMWR Morb Mortal Wkly Rep 2021;70:685688. VAERS reports of syncopal events occurring after receipt of any influenza vaccine administered to persons aged 18 years during the 201920 influenza season (i.e., July 1, 2019June 30, 2020) served as a comparison, because influenza vaccine is similarly administered as a single dose and is available to all U.S. adults. J Neurol. If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. 2021;111:21926. For all four vaccines, pain at the injection. Many Case Report articles were not considered due to the lack of a convincing link between the complication and vaccination. Department of Health and Human Services. Fever. Other tips to combat anxiety over the COVID vaccine: Check your imagination: COVID vaccine anxiety is often fueled by "what-if's"imagined scenarios of the many ways events can head south. Delayed swelling, redness or a rash at the injection site. When I stood, the panic erupted horns blaring. The most commonly reported side effects were: Fever Headache Fatigue (tiredness) Pain at the injection site Helpful tips to relieve side effects Adults To relieve pain or swelling on the arm where you got the shot: Apply a clean, cool, wet washcloth over the area. Contact your healthcare provider. tiredness. For example, a rate of 7.8 syncopal events per 100,000 doses administered was reported after receipt of quadrivalent human papillomavirus vaccine (5). Due to the activity of the immune system, after the injection of COVID-19 vaccines, especially adenovirus-based type, thrombocytopenia, cerebral venous sinus thrombosis, ischemic stroke and intracerebral hemorrhage, have also been reported [27]. 2021;64(1):E1. 2021. https://doi.org/10.1007/s12024-021-00440-7. Ekizoglu E, Gezegen H, Yalnay Dikmen P, Orhan EK, Erta M, Baykan B (2021) The characteristics of COVID-19 vaccine-related headache: Clues gathered from the healthcare personnel in the pandemic. MacNeil JR, Su JR, Broder KB, et al. I'm a teacher and thought maybe my symptoms had something to do with wearing a mask all day. #BestPractices. Assiri SA, Althaqafi RM, Alswat K, Alghamdi AA, Alomairi NE, Nemenqani DM, Ibrahim ZS, Elkady A. These cookies may also be used for advertising purposes by these third parties. Autoimmun Rev. 3501 et seq. Optic neuritis in a patient with seropositive myelin oligodendrocyte glycoprotein antibody during the post-COVID-19 period. ** CDC provided recommendations on who should be vaccinated first because COVID-19 vaccine supply was initially limited. Jain E, Pandav K, Regmi P, Michel G, Altshuler I. Facial diplegia: a rare, atypical variant of Guillain-Barr syndrome and Ad26. However, in order to prove the effectiveness of the vaccine in terms of safety and side effects, the implementation of phase 4 of clinical studies is necessary. Another CDC report released Friday looked at side effects reported by more than 300,000 J&J vaccine recipients. Those with a history of severe allergic reaction (anaphylaxis) to injectables or other vaccines should discuss the vaccination with their doctor, who can evaluate and assess their risk. Forensic Sci Med Pathol. 552a; 44 U.S.C. Loharikar A, Suragh TA, MacDonald NE, et al. Herpes zoster following COVID-19 vaccine: a report of three cases. Dutta S, Kaur R, Charan J, Bhardwaj P, Ambwani SR, Babu S, Goyal JP, Haque M. Analysis of neurological adverse events reported in VigiBase from COVID-19 vaccines. Sect. Vaccines based on mRNA and adenovirus have been reported to be most likely to cause headaches [26]. Acute disseminated encephalomyelitis (ADEM) following recent Oxford/AstraZeneca COVID-19 vaccination. headache. Alshararni A. Typical side effects may include swelling or pain at the point of injection, tiredness, fever or headache, as well as muscular. Nagy A, Alhatlani B. According to published information on the side effects of other adenovirus vaccines, it is essential to properly evaluate the efficacy of the Sputnik vaccine and publish relevant data to decide on its side effects. Anne M. Hause, PhD1; Julianne Gee, MPH1; Tara Johnson, MPH, MS1; Amelia Jazwa, MSPH1; Paige Marquez, MSPH1; Elaine Miller, MPH1; John Su, MD, PhD1; Tom T. Shimabukuro, MD1; David K. Shay, MD1 (View author affiliations). If you receive a J&J vaccine, for three weeks, you should watch for possible symptoms of TTS and get medical help immediately if you have any of these symptoms: According to the CDC, anyone who has a known severe allergy (e.g., anaphylaxis) to any of the vaccine ingredients should not receive that vaccine. These ongoing health problems are sometimes called post-COVID-19 syndrome, post-COVID conditions, long COVID-19, long-haul COVID-19, and post acute sequelae of SARS COV-2 infection (PASC). Manage cookies/Do not sell my data we use in the preference centre. 2021. https://doi.org/10.1136/bmj.n1786. Local Side Effects You may experience pain, redness, and swelling where you got the shot. Venous sinus thrombosis and cerebral hemorrhage are more common in women between the ages of 30 and 50 than in men (Table 2) [8]. Most people have a sore arm right after being vaccinated, and more body-wide effects like fever and chills within 8 to 12 hours. February 27, 2021 / 3:13 PM / CBS Colorado. 1. The first and most common systemic side effect of COVID-19 vaccines is headache, which is mild to severe and is felt in the frontal area of the head. J Neurol. Each type of vaccine can play a different role in increasing the risk of manifestation of these disorders (Tables 2, 3). This was because the population that received Janssen vaccine during its introduction differed from that of the mRNA COVID-19 vaccines because of the prioritization (e.g., by age group, occupation, or underlying health condition) of COVID-19 vaccines. 2021;90(2):3158. MMWR Morb Mortal Wkly Rep 2008;57:45760. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. This virus is known to cause widespread lung infection and hypoxia [1]. We are vaccinating all eligible patients. Neurologia (Barc, Ed impr). Notghi AA, Atley J, Silva M. Lessons of the month 1: Longitudinal extensive transverse myelitis following AstraZeneca COVID-19 vaccination. Postgrad Med J. 2022. https://doi.org/10.1093/qjmed/hcab335. COVID-19 vaccines can cause mild side effects after the first or second dose, including: Pain, redness or swelling where the shot was given Fever Fatigue Headache Muscle pain Chills Joint pain Nausea and vomiting Swollen lymph nodes Feeling unwell Most side effects go away in a few days. Mayo Clinic does not endorse any of the third party products and services advertised. They signal that your immune system is responding to the shot and building up protection against the coronavirus. Mayo Clinic; 2022. Spectrum of neurological complications following COVID-19 vaccination. Ish S, Ish P. Facial nerve palsy after COVID-19 vaccinationA rare association or a coincidence. Curr Cardiol Rep. 2014;16(6):110. The most important and common complicationsare cerebrovasculardisorders including cerebral venous sinus thrombosis, transient ischemic attack, intracerebral hemorrhage, ischemic stroke, and demyelinatingdisorders including transverse myelitis, first manifestation of MS, and neuromyelitis optica. Post-vaccine symptoms are typically mild and resolve quickly without the need to use any medication. Recognizing vaccine-induced immune thrombotic thrombocytopenia. CAS The vaccine cannot cause a COVID-19 infection, so symptoms mean your body is building a healthy immune response. Recommendations for observation after COVID-19 vaccine administration are available at https://www.cdc.gov/vaccines/covid-19/info-by-product/clinical-considerations.html. de Terreros Caro GG, Daz SG, Al MP, Gimeno MM. Blauenfeldt RA, Kristensen SR, Ernstsen SL, Kristensen CCH, Simonsen CZ, Hvas AM. These effects are often acute and transient, but they can be severe and even fatal in a few cases. 2021. https://doi.org/10.1093/qjmed/hcab210. A review of neurological side effects of COVID-19 vaccination, https://doi.org/10.1186/s40001-023-00992-0, https://doi.org/10.1007/s10072-021-05662-9, https://doi.org/10.1038/s41598-022-17514-3, https://doi.org/10.1007/s13760-021-01775-2, https://doi.org/10.9734/ijmpcr/2021/v14i130124, https://doi.org/10.1007/s12024-021-00440-7, https://doi.org/10.1016/j.nrleng.2021.05.002, https://doi.org/10.6061/clinics/2021/e3286, https://doi.org/10.1080/14992027.2021.1931969, https://doi.org/10.1136/postgradmedj-2021-141022, https://doi.org/10.1007/s00415-021-10780-7, https://doi.org/10.1016/j.nrleng.2021.04.002, http://creativecommons.org/licenses/by/4.0/, http://creativecommons.org/publicdomain/zero/1.0/. Indian J Ophthalmol. Among the 64 total cases, 39 (61%) occurred in women. Salinas MR, Dieppa M. Transient akathisia after the SARS-Cov-2 vaccine. Neuroimmunology Reports. Anxiety-Related Adverse Event Clusters After Janssen COVID-19 Vaccination Five U.S. Mass Vaccination Sites, April 2021. and/or the original MMWR paper copy for printable versions of official text, figures, and tables. Finsterer J. All COVID-19 vaccine recipients should be observed for at least 15 minutes after vaccination for anxiety-related and other events (e.g., anaphylaxis or immediate allergic reaction) occurring shortly after vaccination. Increased awareness of anxiety-related events after vaccination will enable vaccination providers to make an informed decision about continuing vaccination. California Privacy Statement, PubMed Its helpful to understand side effects before you get a COVID-19 vaccine. Therefore, vaccination is like a shock to the recurrence of VZV and subsequent herpes zoster [71]. Ghiasi N, Valizadeh R, Arabsorkhi M, Hoseyni TS, Esfandiari K, Sadighpour T, Jahantigh HR. Covid also seems to have a stronger effect on people's neurological and mental health than other respiratory conditions: In the new study, there was overall a 44% greater risk of neurological . 2021;80:34852. The CDC noted that the two mRNA vaccines, from Pfizer and Moderna, are preferred over the Johnson & Johnson vaccine, which remains available for those who prefer it and for use in certain circumstances. All authors have completed and submitted the International Committee of Medical Journal Editors form for disclosure of potential conflicts of interest. Al Khames Aga QA, Alkhaffaf WH, Hatem TH, Nassir KF, Batineh Y, Dahham AT, Shaban D, Al Khames Aga LA, Agha MY, Traqchi M. Safety of COVID-19 vaccines. Google Scholar. Springer Nature. COV2. Second, because the Janssen vaccine is under EUA and health care providers are required to report potentially life-threatening events, a reporting bias might exist. https://www.meddra.org/how-to-use/basics/hierarchyexternal icon, Influenza vaccine doses administered during the 201920 season were estimated based on coverage estimates. Side effects of COVID-19 vaccination have been reported more frequently in people with a history of immune-related diseases or who are more sensitive to age and physiological conditions. For the vast majority of people already vaccinated in the U.S. for COVID-19, the side effects, if any, have been mild. Syncope after vaccinationUnited States, January 2005July 2007. Also, approximately 68.2% of the world's population has been fully vaccinated against this disease. The National Alliance on Mental Health suggest . Most people who get coronavirus disease 2019 (COVID-19) recover within a few weeks. With most of the reactogenic side-effects considered . Users are referred to the electronic PDF version (https://www.cdc.gov/mmwr) Althoughvaccines are now considered the best way to achieve collective safety and control mortality, due to the critical situation, these vaccines have been issued the emergency use licenses andsome of theirpotentialsubsequence side effects have been overlooked. Ogbebor O, Seth H, Min Z, Bhanot N. Guillain-Barr syndrome following the first dose of SARS-CoV-2 vaccine: a temporal occurrence, not a causal association. Allen CM, Ramsamy S, Tarr AW, Tighe PJ, Irving WL, Tanasescu R, Evans JR. Guillain-Barr syndrome variant occurring after SARS-CoV-2 vaccination. The anxiety-related events described here were reported before reports of thrombosis with thrombocytopenia syndrome (7). Int J Med Pharm Case Rep: 20-24. The most important and most common complications are cerebral venous sinus thrombosis (more about AstraZeneca), transverse myelitis (more about Pfizer, Moderna, AstraZeneca, and Johnson & Johnson), Bell's palsy (more about Pfizer, Moderna, AstraZeneca), GBS (more about Pfizer, AstraZeneca, and Johnson & Johnson), and the first manifestation of MS (more about Pfizer). Amyotrophic neuralgia secondary to Vaxzevria (AstraZeneca) COVID-19 vaccine. 2021;85(1):4655. IDCases. Muscle aches. Athyros VG, Doumas M. A possible case of hypertensive crisis with intracranial haemorrhage after an mRNA anti-COVID-19 vaccine. A third reported fever or chills, and about a fifth said they were nauseous. New! Gao J-J, Tseng H-P, Lin C-L, Shiu J-S, Lee M-H, Liu C-H. 2021;14:349. "Please," I pleaded, "can I lie on the floor?". As reported in both studies, the majority of reactions beyond a sore arm happen . Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. Bull-Otterson L, et al. At a Glance People can develop shingles after COVID-19 vaccination, but it's rare. 2021;21(4):4502. This content does not have an English version. Feelings of having a fast-beating, fluttering or pounding heartbeat, Severe or persistent headaches or blurred vision, Easy bruising or tiny blood spots under the skin near the injection site. All information these cookies collect is aggregated and therefore anonymous. Cutaneous reactions reported after Moderna and Pfizer COVID-19 vaccination: a registry-based study of 414 cases. Franchini M, Testa S, Pezzo M, Glingani C, Caruso B, Terenziani I, Pognani C, Bellometti SA, Castelli G. Cerebral venous thrombosis and thrombocytopenia post-COVID-19 vaccination. Reyes-Capo DP, Stevens SM, Cavuoto KM. Other side effects can include pain, redness or swelling at the injection site and possibly headache or nausea, the US Centers for Disease Control and Prevention said. Venous sinus thrombosis is associated with excessive coagulation. Vaccines have always been known to be the most effective and safest drugs; however, different side effects have been identified for them, for example, the link between influenza, hepatitis, and HPV vaccines with demyelinating syndromes has been discovered, and the injection of influenza vaccine is a reason for the incidence of narcolepsy in young people [6]. J Neuroimmunol. See I, Su JR, Lale A, et al. MMWR Morbidity and Mortality Weekly Report. If these side effects occur, they should go away in a few days. The vaccine should slow the spread of COVID-19 around the world. Garca-Azorn D, Do TP, Gantenbein AR, Hansen JM, Souza MNP, Obermann M, Pohl H, Schankin CJ, Schytz HW, Sinclair A. Google Scholar. 2021;121: 102662. Finsterer J, Redzic Z. Symptomatic peduncular, cavernous bleeding following SARS-CoV-2 vaccination induced immune thrombocytopenia. Find more COVID-19 testing locations on Maryland.gov. 2022;75:103293. Why 25-50% of vaccine side-effects are 'anxiety-related and not a result of Covid jab' Anxiety-related reactions comprise symptoms such as vasovagal reaction, when a stressful trigger the sight of blood or syringe causes someone to feel dizzy or faint. volume28, Articlenumber:102 (2023) The Pfizer-BioNTech Covid-19 vaccine is associated with an increased risk of myocarditis, an inflammation of the heart muscle, a large new study from Israel confirms. To hear Shawn Skelton and her fiance tell it, the uncontrollable shaking and tongue spasms she suffered days after taking the Moderna COVID-19 vaccine could only be a. Panic attacks every time I try to get the Covid vaccine. Cookies policy. Saeed BQ, Al-Shahrabi R, Alhaj SS, Alkokhardi ZM, Adrees AO. Olfactory dysfunction ranges from a lack of sense of smell to an olfactory hallucination (phantosmia) that results from a bilateral disturbance or enhancement of the olfactory pathway and the olfactory bulb. 241(d); 5 U.S.C. Post-COVID-19 syndrome. Mayo Clinic Minute: You're washing your hands all wrong. Your Side Effects Don't Go Away iStock If any of the "normal" side effectsincluding pain, redness or swelling in the injection area or fatigue, headache, muscle pain, chills, fever, nauseadon't seem to go away after a few days, you should call your doctor ASAP. Research, Review, and Case Report articles related to adverse effects of COVID-19 vaccination from 2020 to February 2022 were searched and reviewed in Google Scholar, PubMed, and NCBI databases. Chills. Syncope, a common anxiety-related event reported by the five mass vaccination sites, has specific MedDRA preferred terms (syncope and syncope vasovagal) and was the focus of this follow-up investigation. By comparison, 60 reports of syncope after receipt of influenza vaccination were identified during July 1, 2019June 30, 2020 (0.05 episodes of syncope per 100,000 doses of influenza vaccine administered). Erdem N, Demirci S, zel T, Mamadova K, Karaali K, elik HT, Uslu FI, zkaynak SS. 2021;42(10):398990. J Neuroimmunol. 42(45):36675. Vaccine providers should be aware of anxiety-related events after vaccination and observe all COVID-19 vaccine recipients for any adverse reactions for at least 15 minutes after vaccine administration. Women ages 30-49 years, especially, should be aware of the increased risk of this rare adverse event and should know that other COVID-19 vaccines are available.

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